Restenosis has long been a challenge in angioplasty. Drug eluting balloons were designed specifically to address this issue by limiting tissue overgrowth after vessel dilation. Plain balloons reopen blocked arteries but do not prevent the healing response that can cause re-narrowing. DEBs fill that gap by delivering anti-proliferative medication directly into the vessel wall.
The drug coating inhibits smooth muscle cell activation, which is ultimately responsible for excessive tissue buildup. This allows arteries to maintain their widened shape long after the procedure is over. The uniform drug distribution makes DEBs especially effective in small vessels or locations where stenting may not be ideal.
DEBs also work well for treating in-stent restenosis—a situation where a previously placed stent has narrowed again. Instead of implanting additional metal layers, physicians use DEBs to restore vessel patency without increasing rigidity or limiting blood flow.
These balloons embody a less intrusive yet highly efficient method…
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